Common settings
In the case of VMware ESXi 6.X (including 5.X), apply the following updates and KBs.
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VMware ESXi5.5 Update3 and KB2146717
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VMware ESXi6.0 Update2 and KB2145663
Note that you do not need to change the setting value for SCSI Timeout because this value is 140 seconds by default, which is greater than the requirement for a compute node (120 seconds).
Alternate path software setting
No additional settings are required.
Inter-guest cluster setting
For a device in which the inter-guest cluster (MSCS, etc.) uses reserved volumes (SCSI-2, SCSI-3), change "perennially-reserved" to TRUE from each VMware ESXi (see KB). Make this setting irrespective of the storage configuration.
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ESXi/ESX hosts with visibility to RDM LUNs being used by MSCS nodes with RDMs may take a long time to start or during LUN rescan (1016106)
https://kb.vmware.com/s/article/1016106